激光虹膜周邊成形術治療原發性閉角型青光眼急性發作的臨床效果觀察
五官醫學
作者:吳柄東 唐敏
[摘要] 目的 通過探討激光虹膜周邊成形術治療原發性閉角型青光眼急性發作的臨床療效,旨在為有效恢複視力並提高患者生活質量提供理論依據。 方法 選擇2012年1月~2015年1月在我院接受治療的原發性閉角型青光眼急性發作患者150例,患眼150眼,隨機分為研究組和對照組,對照組患者應用小梁切除術治療,研究組患者應用激光虹膜周邊成形術治療,對比兩組患者治療後1個月、3個月、6個月的視力變化及術後1個月、3個月、6個月眼壓變化;同時對比治療後兩組患者房角開放率、中央前房深度、光敏度、中央角膜內皮細胞密度。結果研究組患者術後1個月、3個月、6個月視力水平分別為(0.59±0.09)、(0.61±0.10)、(0.62±0.13),均顯著優於對照組;研究組患者術後1個月、3個月、6個月眼壓分別為(15.07±1.02)mmHg、(14.35±1.01)mmHg、(13.38±1.05) mmHg,均顯著優於對照組,差異有統計學意義(P
[關鍵詞] 激光周邊虹膜成形術;青光眼;閉角型;急性發作
[中圖分類號] R779.63 [文獻標識碼] B [文章編號] 1673-9701(2015)29-0054-04
Clinical effect observation of laser peripheral iridoplasty in treatment of acute attack of primary angle-closure glaucoma
WU Bingdong TANG Min
Department of Ophthalmology, the Affiliated Hospital of Jiujiang University, Jiujiang 332000, China
[Abstract] Objective To explore the clinical efficacy of laser peripheral iridoplasty in the treatment of acute attack of primary angle-closure glaucoma in order to provide theoretical basis for effective eyesight restoration and patients' life quality improvement. Methods A total of 150 patients(150 affected eyes) with acute attack of primary angle-closure glaucoma treated in our hospital from January 2012 to January 2015 were selected and randomly and evenly divided into the study group and the control group. The control group was given trabeculectomy and the study group was given laser peripheral iridoplasty. The posttreatment 1-month, 3-month and 6-month eyesight changes and the posttreatment 1-month, 3-month and 6-month intraocular pressure changes of the two groups were compared. Meanwhile, the posttreatment chamber angle open rates, central anterior chamber depth, light sensitivity and central corneal endothelial cell density of the two groups were compared. Results In the study group, the postoperative 1-month, 3-month and 6-month eyesight levels were (0.59±0.09), (0.61±0.10) and (0.62±0.13) respectively, which were all significantly better than those in the control group. In the study group, the postoperative 1-month, 3-month and 6-month intraocular pressure was (15.07±1.02) mmHg, (14.35±1.01) mmHg and (13.38±1.05) mmHg respectively, which were all significantly better than those in the control group, with statistically significant differences (P
[Key words] Laser peripheral iridoplasty; Glaucoma; Angle-closure; Acute attack
原發性閉角型青光眼急性發作是臨床眼科常見的急症[1],近年來隨著我國老齡化進程的加快導致原發性閉角型青光眼的發病率呈現顯著上升的趨勢,嚴重降低了患者視力,甚至導致患者失明[2],給患者的生活帶來巨大影響。急性發作期患者房角關閉,導致眼壓突然升高,造成視功能不可逆性損傷[3],因此臨床治療以及時降低眼壓為主,現階段治療方式主要有藥物、激光和手術方式[4],藥物治療起效慢、手術治療有一定風險性,激光治療具有操作簡單、見效快速的優點[5],本研究通過應用激光虹膜周邊形成術治療原發性閉角型青光眼急性發作,取得了顯著的臨床療效,現報道如下。
1 資料與方法
1.1 一般資料
選擇2012年1月~2015年1月在我院接受治療的原發性閉角型青光眼急性發作患者150例,患眼150例,隨機平均分成研究組和對照組兩組,每組75例患者,其中研究組男38例,女37例,年齡為57~76歲,平均年齡(66.8±1.1)歲,發作持續時間為4 h~3 d,對照組男36例,女39例,年齡為55~77歲,平均年齡(66.9±1.0)歲,發作持續時間為6 h~4 d,所有患者均確診為急性原發性閉角型青光眼,患者均在急性大發作5 d內,排除並發其他類型青光眼患者,並排除眼部其他疾病及手術史患者,兩組患者在性別、年齡、病情等一般資料方麵比較差異無統計學意義(P>0.05),具有可比性。