兒童蒼耳子中毒致肝衰竭1例分析
病例報告
作者:李永春
[摘要] 蒼耳子是一種中藥材,具有廣泛的藥理作用如抗炎、鎮痛、調節免疫、降血糖、調節血壓等。但如果炮製不當或用量過大可導致中毒,甚至可危及生命。我院消化內科接收1例因食用蒼耳子中毒的患兒.通過采用血液置換、保肝等治療手段進行救治,兩周後患兒臨床指標逐步好轉,患兒痊愈。
[關鍵詞] 蒼耳子;中毒;兒童;肝衰竭
[中圖分類號] R725.9 [文獻標識碼] C [文章編號] 1673-9701(2015)29-0122-03
The analysis of a child liver failure caused by fructus xanthii poisoning
LI Yongchun
Department of Gastroenterology,Children's Hospital of Zhengzhou City,Zhengzhou 450000,China
[Abstract] Fructus xanthii is a kind of traditional Chinese medicine which has wide range of pharmacological effects, such as anti-inflammatory, analgesic, regulating immunity, lowering blood glucose level, regulating blood pressure and so on.But if processed improperly or used excessively can lead poison, even life-threatening. The gastroenterology of children's hospital received a child who was poisoned for eating fructus xanthii. By the plasmapheresis, hepatoprotection and other therapeutic treatments, the child’s clinical indicators had reduced gradually and got well after two weeks.
[Key words] Fructus xanthii;Poisoning;Child;Liver failure
蒼耳子為菊科植物蒼耳幹燥成熟帶總苞的果實,具有祛風散寒、祛風濕、通鼻竅的功能[1],是中醫臨床使用比較廣泛的藥物,多用於治療鼻淵及頭疼病[2,3]。該藥在民間使用也非常廣泛,因此臨床常有成人蒼耳子中毒的病例報道。但兒童蒼耳子中毒的病例並不多見。本例患兒症狀典型,救治及時,預後良好,報道出來供臨床討論。
1 病例資料
1.1 臨床資料
男,3歲,2015年1月20日受涼後發熱,熱峰達38.5℃,熱型不規則,伴流涕、咳嗽症狀;2015年1月21日患兒奶奶喂食患兒蒼耳子果仁(量約一大人手掌)1次,後患兒訴腹痛,具體部位不固定,伴非噴射性嘔吐3次,嘔吐物為白色黏液,至當地靜點藥物1天(用藥不詳),腹痛、嘔吐症狀減輕;4 d前患兒奶奶再次喂食患兒蒼耳子果仁1次,量同前,患兒腹痛、嘔吐症狀反複;於2015年2月3日以“1.蒼耳子中毒;2.膿毒血症;3.中毒性肝炎?”急診收入我院。病來患兒精神差,食欲差,大小便正常。既往史:生後有黃疸史,1個月後消退;無藥物過敏史,疫苗正常接種;無先天性或遺傳性病史。