正文 曲安奈德預防術後增殖性玻璃體視網膜病變患者的臨床分析(1 / 3)

曲安奈德預防術後增殖性玻璃體視網膜病變患者的臨床分析

藥物與臨床

作者:徐洋

[摘要] 目的 探討曲安奈德預防術後增殖性玻璃體視網膜病變的臨床效果。 方法 選取2013年6月~2014年6月視網膜脫離患者60例(均為單眼患病),按隨機數字表法將其分成實驗組30例和對照組30例,兩組病例均行玻璃體切除術。實驗組患者術中預防性應用曲安奈德,對照組患者不應用曲安奈德,比較兩組增殖性玻璃體視網膜病變發生情況。 結果 實驗組增殖性玻璃體視網膜病變發生率為10.0%,術後視網膜脫離複發率為6.7%,術後2mo眼壓≥21 mmHg例數為9例(占30.0%),與對照組相比差異有統計學意義(P

[關鍵詞] 曲安奈德;增殖性玻璃體視網膜病變;預防效果

[中圖分類號] R779.62 [文獻標識碼] B [文章編號] 1673-9701(2015)09-0088-03

Triamcinolone acetonide prevention efficacy of postoperative vitreous of patients with proliferative retinopathy

XU Yang ZHOU Rongkui CUI Haibin HAN Fangfang WANG Dongxia

Department of Ophthalmology,Heilongjiang Eye Disease Prevention and Control Institute in Heilongjiang Province,Harbin 150001,China

[Abstract] Objective To investigate the clinical effects of triamcinolone acetonide prevention of postoperative proliferative vitreoretinopathy. Methods Selected in June 2013-June 2014 60 patients with retinal detachment (both monocular illness),by random number table were divided into experimental group 30 cases and the control group 30 cases, two patients underwent vitrectomy, patients in the experimental group prophylactic triamcinolone acetonide, the control group were not applied triamcinolone acetonide were compared proliferative vitreoretinopathy occurrence. Results The experimental group added vitreoretinopathy rate was 10.0%, postoperative retinal detachment recurrence rate of 6.7%, postoperative IOP≥21 mmHg 2mo number of cases of nine cases(30.0%), compared with the control group, the difference was statistically significant (P

[Key words] Triamcinolone acetonide; Proliferative vitreoretinopathy; Preventive effect

玻璃體視網膜疾病給患者生活質量造成了不同程度的影響,近年來玻璃體手術日趨成熟,用其治療玻璃體視網膜疾病,既能保全眼球,又能不同程度恢複患者視力,曲安奈德注射治療玻璃體視網膜疾病可收獲較佳的療效及安全性。有文獻顯示[1],對玻璃體視網膜手術患者術中應用曲安奈德,術中可快速分辨玻璃體,促進殘留皮質切除,減少手術時間,提高手術成功率;此外,曲安奈德具有較強的抗增殖、抗炎作用,可降低增殖性玻璃體視網膜病變率及視網膜脫離複發率。本研究選擇2013年6月~2014年6月間對30例玻璃體切除術患者術中應用曲安奈德,效果十分滿意,現報道如下。