HCV漏檢會涉及到醫院性感染的責任問題,聯合HCV-cAg檢測就很有必要,會更有利於窗口期更長、免疫受抑的血液透析患者的篩選。並且開展HCV-cAg的ELISA檢測,其操作與目前檢測HCV 抗體類似。操作簡便,成本相對較低,而且無特殊設備要求,基層實驗室均能開展,宜於普及篩查。聯合檢測抗-HCV抗體和HCV-cAg可起到互補作用,提高陽性檢出率[17],比單測抗-HCV抗體更能降低這些風險。血液透析醫院加強患者透析前的嚴格篩查分級、做好基礎衛生防護、嚴格遵守感染控製措施、執行嚴格的規範操作、開展針對醫護人員和病人的教育計劃、手部衛生、透析機的維護和消毒、醫療物品一次性使用和廢棄物的管理等對降低血透患者丙型肝炎感染率也是非常重要的。
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(收稿日期:2014-11-25)