立體定向伏隔核毀損術治療酒精依賴患者術後健康狀況及生存質量調查
臨床研究
作者：張偉等
[摘要] 目的 調查立體定向伏隔核毀損術治療酒精依賴患者術後健康狀況及生存質量。 方法 選擇在第四軍醫大學唐都醫院行立體定向伏隔核毀損術治療酒精依賴患者31例為研究對象，術後1年對患者進行隨訪調查，了解患者術後的健康狀況以及生存質量，分析該手術方法的安全性和有效性。 結果 1年內戒斷率90.3%（28/31）。治療後自我感覺健康狀況較術前良好19例，占61.3%，感覺較術前好了一些10例，占32.3%，覺得和術前差不多2例，占6.5%，無自我感覺健康狀況較術前差的患者。健康狀況問卷調查結果顯示患者術後12個月生理機能、生理職能、軀體疼痛、一般健康狀況、情感職能、精神健康等各領域得分均較術前顯著升高（P
[關鍵詞] 立體定向伏隔核毀損術；酒精依賴；健康狀況；生存質量
[中圖分類號] R749.62 [文獻標識碼] B [文章編號] 1673-9701（2015）09-0060-03
A survey on postoperative health conditions and life quality for patients with alcohol dependence treated by stereotactic lesioning of nucleus accumbens
ZHANG Wei1 HUANG Ziye1 SHA Jianmin1 GAO Guodong2 DU Jiang3
1.Department of Psychiatry， Wenzhou Seventh People's Hospital， Wenzhou 325006， China； 2.Department of Neurology， Tangdu Hospital of the Fourth Military Medical University， Xi’an 710038， China； 3.Department of Neurology， Shanghai Mental Health Centre， Shanghai 200030， China
[Abstract] Objective To investigate postoperative health conditions and life quality for patients with alcohol dependence treated by stereotactic lesioning of nucleus accumbens. Methods All 31 patients with alcohol dependence who received stereotactic lesioning of nucleus accumbens in Tangdu Hospital of the Fourth Military Medical University were selected as research subjects. Follow-up investigation was carried out for patients one year after the surgery. Patients' postoperative health conditions and life quality were understood， so as to analyze the safety and effectiveness of the surgical procedure. Results The abstinence rate within one year was 90.3%（28/31）. 19 patients felt that their health conditions after the surgery were much better than those before the surgery， accounting for 61.3% of the total patients. 10 patients felt that their health conditions after the surgery were somewhat better than those before the surgery， accounting for 32.3% of the total. 2 patients felt that their health conditions were the same as those before the surgery， accounting for 6.5% of the total. No patients felt that their health conditions were worse than those before the surgery. Results of the questionnaire on health conditions showed that scores of physiological function， role physical， physical pain， general health condition， role emotional， mental health and other domains within 12 months after the surgery were all significantly higher than those before the surgery （P
[Key words] Stereotactic lesioning of nucleus accumbens； Alcohol dependence； Health conditions； Life quality