正文 多層螺旋CT灌注成像對肝髒占位性病變的診斷與鑒別診斷(1 / 3)

多層螺旋CT灌注成像對肝髒占位性病變的診斷與鑒別診斷

放射與影像

作者:毛景鬆

[摘要] 目的 利用多層螺旋CT灌注成像對肝髒腫瘤樣病變進行診斷及鑒別診斷。 方法 先行多層螺旋CT進行灌注掃描,獲得圖像傳至ADW 4.3工作站,利用Perfusion 3軟件進行重建,把腹主動脈做為輸入動脈,下腔靜脈做為輸出動脈,選定合適的感興趣區域,得到灌注圖像及灌注參數,計算出BF、 BV、 MTT、 PS 和HAF各參數圖中的參數值,利用統計學軟件,進行分析。 結果 肝癌組、肝血管瘤組、肝轉移瘤組BF、HAF明顯高於正常組(P

[關鍵詞] 肝癌;肝轉移瘤;肝血管瘤;多層螺旋CT;肝髒灌注成像

[中圖分類號] R735.7;R816.5 [文獻標識碼] B [文章編號] 1673-9701(2015)09-0091-03

Multi-slice spiral CT perfusion imaging in diagnosis and differential diagnosis of focal liver lesions

MAO Jingsong

Department of Radiology, Shenyang Fifth People's Hospital, Shenyang 110023, China

[Abstract] Objective To diagnose and distinguish diagnosis of focal liver lesions by multi-slice spiral CT perfusion imaging. Methods Images obtained by multi-slice spiral CT perfusion scan were transmitted to AW4.3 workstation. Perfusion 3 software was used for reconstruction, with the abdominal aortic artery as input and the inferior vena cava artery as output. The appropriate region was selected for obtaining the perfusion images and perfusion parameters. The values of BF, BV, MTT, PS and HAF were calculated, and then they were analyzed by statistical software. Results The values of BF and HAF in liver cancer group, hepatic hemangioma group and hepatic metastasis group were significantly higher than those in normal liver tissue (P

[Key words] Liver cancer; Hepatic metastasis; Hepatic hemangioma; Multi-slice spiral CT; Liver perfusion imaging

肝髒好發原發及轉移的惡性腫瘤,原發性肝癌是最普通的惡性腫瘤之一,並且有不斷增加的趨勢,早期診斷尤為重要。CT灌注成像是一種定量分析組織的血流灌注,可用於評價組織的解剖及形態學。對於腫瘤的灌注正在不斷的增加認識和應用。近年來,隨著多層螺旋 CT 機的出現,掃描速度、數據采集、圖像重建等方麵均有極大改善。目前的灌注掃描由傳統的單室模型發展到開放式四室模型,增加了新的評價指標,並可通過色階賦值形成灌注影像,從而更加全麵、直觀地了解髒器及病變的血流灌注特點及血管特性,反映組織生理功能的改變,從而達到功能性診斷的目的,同時,國內外不少學者把CT灌注成像應用於肝髒疾病治療的評定及療效的評估。本研究收集我院2014年1~11月共23例肝髒惡性腫瘤、10例血管瘤及12例正常肝組織,進行CT灌注掃描,根據灌注參數及灌注彩圖,對腫瘤樣病變進行診斷及鑒別診斷的探討。